Scores of Asian and Western countries have recognized curriculum leadership in schools as the key to bringing about effective school-based curriculum change. Improvements to the curriculum help students enhance their learning and help them adapt better to the changing society. The notion of curriculum leadership in schools first emerged in the last decade, when the responsibility for curriculum development shifted to individual schools. Public concern about the quality of student performance and achievement in schools has gradually grown. As a result, there has been a general call for a reinvigoration of the teaching workforce and for teachers to become leaders in the school curriculum. In this chapter, the conceptualized characteristics of curriculum leadership in schools are elucidated. In addition to analyzing the practice of curriculum leadership in school-based curriculum development, the chapter also discusses the importance of changing school cultures to sustain curriculum leadership in schools. Last but not least, through a detailed case study, it looks into how a curriculum leader establishes a positive working relationship with the school principal.